The science behind
your genes
Genomics explained without the hype. Evidence-based articles on pharmacogenomics, nutrigenomics, genetic privacy, and making sense of your raw DNA data.
Download 23andMe Raw Data 2026: Yes, Even After Bankruptcy
Read Your 23andMe File With Claude, Without Uploading It
Ask Claude about your 23andMe raw data while the file stays on your computer. A free local package reports curated positions; the file never reaches DeepDNA.
Whole Genome Sequenced and Never Used? What to Do With It
What to do with whole genome sequencing data: what to ask it once, how it changes the reading of your bloodwork, what long reads add, what it can't predict.
The 23andMe API Is Gone: Reading 23andMe Data in Python
The 23andMe API was switched off in 2018 and api.23andme.com now redirects away. Read the raw data file in Python instead: format, pitfalls, GRCh38 remap.
A Pharmacogenomics MCP Server for Claude, Cursor and VS Code
Give your AI agent cited drug–gene records, most from CPIC and DPWG, instead of recall. One line to connect, no key: a medication screen and rsID lookups.
PharmGKB API Not Working? Migrate to ClinPGx in Python
PharmGKB API calls failing? api.pharmgkb.org no longer resolves. Move to api.clinpgx.org in Python with a 2 req/s throttle, loud errors and CPIC renames.
CYP2C19 and SLCO1B1 From a Raw DNA File in Python
Parse a 23andMe or AncestryDNA raw file, count CYP2C19 and SLCO1B1 marker alleles, see why that is not a clinical phenotype, and fetch cited drug guidance. Working code.
What Your AI Agent Needs to Know About Your Blood Test
A lab report is a PDF, not data. Here is why an agent reading it from memory gets the reference range wrong, what structured biomarkers look like, and how DNA and bloodwork read together.
How to Let Your AI Agent Read Your DNA Without Handing It Your Genome
You have a raw DNA file and an AI agent. Here is what the agent should do, what a tool should do instead, what you can try today for free, and the five questions to ask before any upload.
Can ChatGPT Analyze Your Raw DNA Data? What Actually Works
ChatGPT can't read a 600,000-SNP file. Here's what happens when you try, the 3 errors it makes on one variant, and what actually works.
AncestryDNA Raw Data: Download and Analyze It (2026)
Your AncestryDNA raw data holds ~700,000 genotyped positions that Ancestry never interprets for health. How to download the file and analyze it yourself.
CRISPR 2026: What Gene Editing Can Actually Treat
One approved therapy, the first successful in-body trial, and the delivery problem holding back the rest — where CRISPR stands in 2026.
Single-Cell RNA-Seq Analysis with AI: Tools and Best Practices
How to analyze single-cell RNA-seq data using AI tools like scGPT, Geneformer, Scanpy, and Seurat. A practical guide to the 2026 scRNA-seq workflow.
AlphaFold Impact on Drug Discovery Timelines
How AlphaFold compresses the structure step in drug discovery: the months-long bottleneck it removes, how Isomorphic and Recursion use it, and its limits.
Protein Language Models: The LLM Moment for Biology
ESM-2, ProtTrans and ProGen2 are protein LLMs — foundation models that read protein sequences like language to predict structure, function and evolution.
AI in Genomics: How Machine Learning Transforms DNA Analysis
How AI and machine learning are transforming genomics — from DeepVariant's variant calling to AlphaFold's protein predictions. What it means for your DNA.
COMT Val158Met: The Warrior/Worrier Idea and the Evidence
COMT Val158Met (rs4680) changes enzyme activity 3- to 4-fold. What studies report for groups, why the effects are small, and why warrior/worrier is a hypothesis.
Night Owl or Lark? Chronotype Is 47% Genetic
Night owl or morning lark? Chronotype is up to 47% genetic. See how PER2, CRY1, and CLOCK variants in your DNA set your sleep timing and ideal schedule.
VDR Gene: Why Some People Need More Vitamin D Than Others
The VDR gene controls how your body uses vitamin D. Variants like FokI and BsmI affect receptor function, deficiency risk, and supplementation response.
ACTN3 Gene (R577X): What RR, RX and XX Mean
The ACTN3 gene builds a protein found only in fast-twitch muscle fibers. What the R577X variant means if you are RR, RX or XX — for sprint power and endurance.
FTO Gene and Weight: What Genetics Really Says About Obesity
The FTO gene is the strongest genetic link to body weight — but it's not what you think. Here's what your FTO variant actually does and why it's not destiny.
Is Lactose Intolerance Genetic? The LCT Gene Explained
Is lactose intolerance genetic? Yes — rs4988235 near the LCT gene shapes whether you digest milk as an adult. About 68% of adults worldwide do not.
CYP1A2 and Caffeine: What rs762551 Can and Can't Tell You
What the CYP1A2 rs762551 genotypes (AA, AC, CC) are associated with, what they cannot tell you about your own caffeine half-life, and the heart risk research.
Polygenic Risk Scores Explained: Should You Care?
A polygenic risk score combines thousands of DNA variants into one number. Learn what PRS can and cannot predict and its limits. 2026 guide.
How DNA Testing Works: Saliva to Insights
Learn how DNA testing works — from saliva collection to SNP genotyping and results. Understand the science behind consumer genetic tests.
Nutrigenomics Guide 2026: What Diet Genes Can and Can't Tell You
MTHFR, FTO, LCT, CYP1A2: what the evidence says about diet-related gene variants, and why none of them sets a personal diet. 2026 guide for raw DNA data.
What Are SNPs? The Tiny DNA Variants That Shape Your Health
SNPs are the most common genetic variants in your DNA. Learn what single nucleotide polymorphisms are, how they affect health, and why SNP analysis matters.
What Is DNA Analysis? Meaning, Methods and Costs
DNA analysis reads the variants in your genome to reveal traits, drug response and health risk. SNP genotyping vs whole genome sequencing — methods and costs.
MTHFR Gene: What Your Variant Actually Means
The MTHFR gene is one of the most searched genetic variants. Here's what C677T and A1298C really mean for your health, based on evidence.
Pharmacogenomics in Europe: DNA and Drug Response
Your genes influence how you metabolize medications. Learn about CYP2D6, CYP2C19, and why pharmacogenomics testing matters in Europe.
GDPR & Genetic Data: 9 Rights You Have in 2026
Your DNA is special-category data under GDPR Art. 9. Learn the 9 rights EU citizens have over genetic data, and how to enforce them in 5 minutes.
Best 23andMe Alternatives in Europe (2026)
Looking for a European alternative to analyze your 23andMe raw data? We compare Promethease, SelfDecode, Genomelink, and more.
10 Best Bioinformatics Tools for Genomic Analysis (2026)
The 10 best bioinformatics tools for genomic data analysis in 2026. From BLAST to Galaxy to DeepVariant — real use cases, honest pros and cons, and what actually works.
Spatial Transcriptomics: Mapping Gene Expression in Tissue
Spatial transcriptomics maps gene expression directly in tissue, preserving where each gene is active. A plain-language guide to Visium, MERFISH, and how spatial genomics is transforming cancer research and drug discovery.
Whole Genome vs Exome Sequencing: Which One Do You Need?
WGS sequences all 3 billion base pairs. WES targets only the 1-2% that code for proteins. Which one fits your research or clinical goals? A practical comparison with decision flowchart.
DeepDNA is now an API.
Not a report to buy: cited records for the agents and apps you use, live and free, no key. A free local package reads the curated positions of a raw DNA file on your own computer. Parsing DNA files and lab reports on our servers, and crossing the two, is in private beta. Read the API docs.